Functional antibodies

Defects in functional antibody responses to vaccination are associated with primary antibody deficiency e.g. common variable immunodeficiency. A defect of functional antibody responses, with normal Ig levels, is of debatable significance. Low levels should be tested by repeating 4 weeks after vaccination. May be used to assess risk of vaccination (high titre). Please phone for advice or consider referral to clinical immunology clinic.

Other Comments:

HiB = >0.15 ug/ml Tetanus = >0.1 IU/ml Pneumococcal = >0.35 ug/ml