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Voltage-gated Calcium Channel Antibody

About This Test

Department: Immunology

Requirement: None

Turnaround Time: 21 days

The assay is positive in approximately 85% of patients with the Lambert Eaton myasthenic syndrome (with or without small cell lung carcinoma SCLC) and in about 30% of Cerebellar ataxia with SCLC. Calcium channel antibodies are rarely found in patients without myasthenic symptoms, except at low titre in a few cases with small cell lung cancer. This is because small cell lung cancers express this voltage gated calcium channel.

Other Comments:

•Negative =